Cyclobenzaprine: What Is It? Side Effects & Interactions Cleveland Clinic

Flexeril is a pain reliever that is widely taken to relieve muscle spasms and improve motor abilities, sleep, and energy levels. As a result, the activity of Cyclobenzaprine (Flexeril), which depresses the Central Nervous System and causes these sensations, could be a reason for Flexeril misuse and addiction. In conjunction with physical therapy and rest, the muscle relaxer Flexeril treats skeletal muscle conditions such as pain, strains, injuries, sprains, or spasms.

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We have everything you need to come off safely, from talk therapy to medication-assisted treatment. We’ll consider your unique circumstance when administering specialized treatment aligned with your individual needs and expectations. A Flexeril overdose can occur if too much of the drug is consumed. The standard cyclobenzaprine dosage depends on the medication’s type and whether the patient is an adult or a child.

FDA Drug Information

Blood chemistry tests (including thyroid-stimulating hormone at screening only), hematology tests, and urinalysis were performed at screening and on Days −1 and 56. Serum ß-human chorionic gonadotropin measurement was performed on women of childbearing potential at screening and on Days −1 and 56. Laboratory tests with values that became clinically significantly abnormal after drug administration were repeated until the values returned to normal or the etiology was identified and the sponsor notified.

Polydrug abuse can cause serious harm, especially when the combination includes CNS depressing substances such as benzodiazepines and alcohol. It is also possible for serious cyclobenzaprine side effects to occur, like seizures, heart arrhythmias, heart attack, or stroke. These are more likely to occur when a person has too much cyclobenzaprine in their system, for instance, if their prescription dose is too high or if they are misusing the drug. It is recommended to not drive or operate heavy machinery when under the influence of muscle relaxers.

• Based on the findings, FLEXERIL should be used with caution in subjects with mild hepatic impairment starting with the 5 mg dose and titrating slowly upward.
• Blood chemistry tests (including thyroid-stimulating hormone at screening only), hematology tests, and urinalysis were performed at screening and on Days −1 and 56.
• Use of FLEXERIL for periods longer than two or three weeks is not recommended.
• Tell your doctor if you are pregnant or plan to become pregnant during treatment with Flexeril.
• If your story is chosen, a member of our team will reach out to you.

Our Montecito treatment and therapy options include many alternative and modern therapeutic options. Our overall goal is, and always will be, your overall health and wellness; this includes a commitment to your mental, physical, and spiritual wellbeing. We take pride in our ability to help you regain control over your life. As a result, if the half-life of Flexeril is eight hours, it will take just under two days for the body to eliminate the drug.

Common Cyclobenzaprine Side Effects

This can be harmful or prevent the drug from working well. Within the last five years, emergency room department visits related to muscle relaxant abuse almost doubled; they increased from 15,830 to 31,763 visits. Unlike a few other muscle relaxers, it’s currently not controlled under the Controlled Substances Act. No matter how hard they try to avoid them, many people suffer from muscular injuries, whether muscle sprain, strain, chronic back pain, etc. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. If you think you may have taken too much cyclobenzaprine and are at risk of an overdose, you may exhibit the following symptoms and need to call 911 immediately.

As management of overdose is complex and changing, it is recommended that the physician contact a poison control center for current information on treatment. Signs and symptoms of toxicity may develop rapidly after cyclobenzaprine overdose; therefore, hospital monitoring is required as soon as possible. The acute oral LD50 of FLEXERIL is approximately 338 and 425 mg/kg in mice and rats, respectively. In addition, the VLD CBP and placebo groups were compared using change from baseline at Week 8 using a 2-sample t test with a 2-sided p value.

In patients with CNS depression, early intubation is advised because of the potential for abrupt deterioration. Seizures should be controlled with benzodiazepines or, if these are ineffective, other anticonvulsants (e.g. can you take methocarbamol with flexeril phenobarbital, phenytoin). Physostigmine is not recommended except to treat life-threatening symptoms that have been unresponsive to other therapies, and then only in close consultation with a poison control center.

Sometimes people will even have a heart attack or develop seizures. In order to quit safely, you need to opt for professional Flexeril rehab. Getting treated for your Flexeril addiction professional has so many benefits.

Understanding Flexeril (Cyclobenzaprine)

It is also sometimes prescribed off-label to treat fibromyalgia pain. Most inpatient and outpatient rehab programs include cognitive behavioral therapy that will help you learn the coping skills needed for long-term recovery. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medication affects you. Do not stand or sit up quickly, especially if you are an older patient. Alcohol may interfere with the effect of this medication.